The genetics of axonal transport and axonal transport disorders.

The genetics of axonal transport and axonal transport disorders.

Blog Article

Neurons are specialized cells with a complex architecture that includes elaborate dendritic branches and a long, narrow axon that extends from the cell body to the synaptic terminal.The organized transport of essential biological Inflammatory Health materials throughout the neuron is required to support its growth, function, and viability.In this review, we focus on insights that have emerged from the genetic analysis of long-distance axonal transport between the cell body and the synaptic Collections terminal.

We also discuss recent genetic evidence that supports the hypothesis that disruptions in axonal transport may cause or dramatically contribute to neurodegenerative diseases.